Lyra and ICAS unite under one brand to set a new global standard for workforce mental health.
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Mental health care grounded in science

Explore our methodology

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Many treatments practiced today are ineffective. Lyra only delivers the most effective care.

Health Plans vs. Lyra82.7% improved or recovered with Lyra

With health plans…

Only 24% of members who receive care through health plans demonstrate reliable clinical improvement.

With Lyra…

88% of members improve or recover.

How is improvement measured?

Lyra uses validated clinical measures, such as the PHQ-9 and the GAD-7, to assess symptom improvement for anxiety, depression, and other common mental health issues. Reliable clinical change is a 6-point difference on the PHQ-9 and a 4-point change on the GAD-7.

The gold standard of measuring improvement

No vanity metrics. Only meaningful, measurable change.

At Lyra, we use “reliable clinical improvement” to measure change, which means that an individual in treatment has improved enough on a measure of clinical symptoms that we don’t believe the change can be accounted for by normal variation in scores or measurement error.

Other companies often report a 1-point change, which represents normal variation in symptom scores over time and does not reflect a meaningful improvement in depression, anxiety or stress.

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Grounded in proven treatment methods

Evidence-based treatments, or EBTs, are methods that have been proven effective at reducing symptoms and overall functioning, as defined by the Division of Clinical Psychology of the APA (Chambless & Hollon, 1998; Tolin et al., 2015). Lyra only works with providers who provide these treatments.

Common characteristics of EBTs

  • Goal-focused treatment
  • New skill development
  • Practice between sessions
  • Track progress toward goals
  • Short-term and long-lasting results

Results from Lyra’s latest clinical research

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ESTs effective in real-world settings

Results from the study of more than 1,200 Lyra clients showed that evidence-supported therapies (ESTs) are effective at treating anxiety and depression – even outside of highly controlled laboratory settings.

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Blended Care Therapy helps clients recover faster

A study of Lyra’s Blended Care Therapy program, that combines video therapy sessions with personalized digital tools, reveals it’s effective for treating depression and anxiety and can help clients recover two to three times faster than CBT alone.

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Coaching effective for treating stress

Study published in the journal Telemedicine and eHealth shows Lyra’s Cognitive Behavioral Coaching program is effective at reducing stress and that participants who started with particularly high stress improved at even higher rates.

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Our recent studies and viewpoints

With thousands of members using Lyra and the largest network of evidence-based providers, we can glean some amazing insights into treatment and provider effectiveness. Read the latest findings from our clinical research team.

Benefits Professional

Are Evidence-Based Therapies Effective in the Real World? New Research Says Yes

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Benefits Professional

The Lack of Evidence-Based Therapies in Health Plan Networks

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Our nationwide network, built with the highest quality standards

Thousands of providers across all 50 states offer evidence-based treatments and are specifically recruited to give your employees the highest quality care and diverse options for race/ethnicity, LGBTQ sensitivity, and clinical focus.

Designed by the brightest clinical experts

Our mission and vision is guided and designed by leading clinical experts in evidence-based methods who collectively have 60 years of experience, dozens published academic papers, and serve on prestigious committees in their field.


Dr. Connie Chen

Chief Medical Officer

  • BA in Economics at Harvard
  • MD from UCSF
  • Board-Certified, Internal Medicine (Stanford)
  • Published in the Journal of the American Medical Association (JAMA)
  • Board of Overseers at UCSF

Dr. Bob Kocher

President, Lyra Clinical Associates PC

  • Adjunct Professor of Medicine at Stanford University School of Medicine
  • Non-Resident Senior Fellow at the USC Schaeffer Center for Health Policy
  • Served in the Obama Administration as Special Assistant to the President for Healthcare and Economic Policy
  • MD from the George Washington University and BS from the University of Washington
  • Internal Medicine training at the Beth Israel Deaconess Medical Center

Dr. Smita Das

Medical Director of Psychiatry

  • BS in Statistics and Chemistry from Stanford University; MPH with focus on clinical quality from Dartmouth College; MD and PhD from University of Illinois in Community Health with a focus on behavioral change in healthcare systems
  • Adult Psychiatry Residency at Stanford School of Medicine and Addiction Psychiatry Fellowship at UCSF
  • Clinical Assistant Professor at Stanford School of Medicine
  • Widely published and national leader and in policy for addiction and psychiatry, for example at the American Psychiatric Association